Acne is normal, everyone gets it. Blemishes can show up for various reasons: hormone fluctuation, stress, and diet changes are just some of the reasons we get acne.

To help get rid of stubborn or unexpected zits, we’ve rounded up some of the best acne spot treatments that are highly effective in shrinking or getting rid of your most stubborn acne spots.

Ultimate Stinky Pimple Treatment, Dr. Barbara Sturm, $45

Formulated with shale oil – which is anti-microbial, tiger grass – which is soothing, hyaluronic acid, and pre, and probiotics, this spot treatment is perfect for people with oily skin, large pores, or who are prone to experiencing breakouts. You can apply the Stinky Pimple Treatment as a spot treatment or as an overnight mask.

LHA Serum, SkinCeuticals, $132

SkinCeuticals LHA Serum is an oil-free treatment that’s gentle enough to use on the entire face. Made using salicylic acid, glycolic acid and dioic acid (naturally derived from vegetables), this serum reduces excess sebum production which can clog pores. 

Alpha Beta® On The Spot Eliminator, Dr. Dennis Gross, $54

This concentrated spot treatment clears and prevents blemishes while smoothing skin and minimizing fine lines. Using a high dose of salicylic acid, the Alpha Beta® On The Spot Eliminator is combined with glycolic acid and azelaic amino acid to treat white and blackheads.

Posay Effaclar Duo+, La Roche, $31

Effaclar Duo+ works to treat acne without drying you out. Tested to be safe on sensitive skin and approved by dermatologists, this hydrating gel cream can be used as a spot treatment or on the entire face.

Super Spot Remover™, Origins, $29

This acne treatment gel is formulated with salicylic acid and witch hazel extract to target stubborn spots and absorb excess oil. Use your fingers or a Q-Tip to dab the gel directly on to any blemishes.